For research use only · Not for human consumption · COA available on request
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New in the library · Research use only

Retatrutide.

A triple agonist at GLP-1, GIP, and glucagon receptors — lyophilized for scientific research applications. Third-party tested to 99.4% purity.

99.4%
HPLC purity
5 mg
Vial size
ISO
Certified labs
≤24h
COA dispatch
Retatrutide lyophilized peptide vial

What it is

Three receptors. One molecule.

01
GLP-1Glucagon-like peptide-1

Insulin secretion. Glucose homeostasis. Slowed gastric emptying. The most-studied agonist class in modern metabolic research.

02
GIPInsulinotropic polypeptide

Glucose-dependent insulinotropic polypeptide. Receptor activation that complements GLP-1 with distinct downstream effects on adipose tissue.

03
GlucagonGlucagon receptor

Activation of the glucagon receptor — distinct from the others — drives energy expenditure pathways in preclinical models.

Verification

What goes in. And why.

Every batch of retatrutide is verified by ISO-certified third-party laboratories. Identity confirmed by mass spectrometry. Purity assessed by HPLC. Endotoxin and sterility tested before release.

  • Identity confirmed by mass spectrometry
  • Purity assessed by reverse-phase HPLC
  • Endotoxin tested to <0.05 EU/mg
  • Sterility verified before release
Request the full COA →

Certificate of Analysis

BatchFPL-RTA-26-001
IdentityConfirmed (MS)
Purity99.4% (HPLC)
Endotoxin<0.05 EU/mg
SterilityPass
Issued12 June 2026

Peer-reviewed literature

What the literature says.

[01]
NEJM · 2023
Jastreboff et al. — Triple-Hormone-Receptor Agonist Retatrutide for Obesity: A Phase 2 Trial

Phase 2 randomized trial reporting receptor activation profile and dose-response data.

Read summary →
[02]
Mol Metab · 2022
Coskun et al. — LY3437943, a novel triple GIP/GLP-1/glucagon receptor agonist

Mechanism characterization and preclinical efficacy data.

Read summary →
[03]
Diabetes Care · 2024
Review — The emerging class of multi-receptor incretin agonists

Overview of the receptor pharmacology landscape including retatrutide.

Read summary →

Handling

Storage. Handling. Stability.

Storage

  • Store lyophilized vials at −20°C, protected from light.
  • Short-term storage at 2–8°C is acceptable prior to reconstitution.
  • Avoid repeated temperature cycling of sealed vials.

Reconstitution

  • Reconstitute with bacteriostatic water for research preparations.
  • Introduce solvent along the vial wall; do not agitate vigorously.
  • Allow the powder to dissolve fully before handling.

Stability

  • Lyophilized form is stable for extended periods when stored correctly.
  • Reconstituted solutions are stored refrigerated at 2–8°C.
  • Lyophilization preserves peptide integrity during transit.
Retatrutide
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